If your goal is protecting confidential files on a flash drive, thumb drive, memory card, or external USB disk, the best USB encryption software should secure the removable drive itself instead of only locking selected folders.
1. You want to encrypt a removable drive rather than only lock one folder.
2. You need a secure encrypted area plus a normal public area on the same device.
3. You carry work files, client data, travel documents, or personal backups on USB media.
Use File Lock Pro when you only need folder-level locking on a USB drive. Use USB Lock when you need USB port policy and device control instead of encrypted storage.
For most users searching "best USB encryption software," GiliSoft USB Encryption is the stronger fit when the real goal is password-protected data security on the removable drive itself.